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DDX11 / CHLR1

DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitment of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.

Gene Name: DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Family/Subfamily: DEAD box protein
Synonyms: DDX11, CHL1-related helicase gene-1, CHLR1, CHL1-related protein 1, CHL1-like helicase homolog, KRG2, WABS, DEAD/H box protein 11, HCHLR1, KRG-2
Target Sequences: NM_030653 NP_085911.2 A8MPP1

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Proteins (3)
Recombinant (3)
DDX11 / CHLR1 (3)
No (3)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Human (3)
E. coli (1)
Wheat Germ Extract (2)
Purified (1)
DDX11 / CHLR1 Protein - Recombinant  Cell Adhesion Molecule With Homology To L1CAM By SDS-PAGE
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E. coli
His-T7
37.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
DDX11 / CHLR1 Protein - 12.5% SDS-PAGE of human DDX11 stained with Coomassie Blue
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Wheat Germ Extract
GST
132.46 kDa
10 µg/$479; 25 µg/$670
DDX11 / CHLR1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-3 of 3 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).