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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DDC / DOPA Decarboxylase

dopa decarboxylase (aromatic L-amino acid decarboxylase)

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: dopa decarboxylase (aromatic L-amino acid decarboxylase)
Family/Subfamily: Carboxy-lyase , Not assigned-Other
Synonyms: DDC, AADC, DOPA decarboxylase
Target Sequences: NM_000790 NP_000781.1 P20711

Publications (1)

1
Dopamine synthesis and dopamine receptor expression are disturbed in recurrent miscarriages. Gratz MJ, Stavrou S, Kuhn C, Hofmann S, Hermelink K, Heidegger H, Hutter S, Mayr D, Mahner S, Jeschke U, Vattai A. Endocrine connections. 2018 May;7:727-738. (Human) [Full Text Article] [PubMed:29686031] [PMC:PMC5958746] Related Antibodies: LS-B10123.

Filtered by: None
Type
Custom (10)
Sandwich (3)
Sandwich CLIA (1)
Target
DDC / DOPA Decarboxylase (14)
Reactivity
Human (6)
Mouse (1)
Rat (1)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Sample Type
Cell Lysates (2)
Plasma (2)
Serum (2)
Tissue Homogenates (2)
Publications
No (14)
Showing 1-14 of 14 results

Human DDC / DOPA Decarboxylase ELISA Kit (Sandwich ELISA) - LS-F7499
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Human DDC / DOPA Decarboxylase ELISA Kit (Sandwich ELISA) - LS-F21062
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Bovine DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F17252
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Mouse DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F17254
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Rat DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F17253
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F17255
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Pig DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F17256
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Monkey DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F43345
Custom
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Chicken DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F43344
Custom
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Porcine DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F43346
Custom
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Rabbit DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F43348
Custom
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Human DDC / DOPA Decarboxylase ELISA Kit (CLIA) - LS-F29795
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human DDC / DOPA Decarboxylase ELISA Kit (Custom ELISA) - LS-F50221
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human DDC / DOPA Decarboxylase ELISA Kit (Sandwich ELISA) - LS-F54950
Sandwich
96-Well Strip Plate
Human
25 - 1600 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1plate  $870.00
LSBio image for ELISA Kit
Showing 1-14 of 14 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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