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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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DCK / Deoxycytidine kinase
deoxycytidine kinase
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Clinicopathological significance of deoxycytidine kinase expression in esophageal squamous cell carcinoma. Shimada Y, Okumura T, Sekine S, Moriyama M, Hojo S, Matsui K, Sawada S, Nagata T, Fukuoka J, Tsukada K. Molecular and clinical oncology. 2013 1:716-720. (IHC; Human)[Full Text Article]
[PubMed:24649234]
[PMC:PMC3915311]
Related Antibodies: LS-B1825.
2
The augmented expression of the cytidine deaminase gene by 5-azacytidine predicts therapeutic efficacy in myelodysplastic syndromes. Murakami Y, Kimura Y, Kawahara A, Mitsuyasu S, Miyake H, Tohyama K, Endo Y, Yoshida N, Imamura Y, Watari K, Ono M, Okamura T, Kuwano M. Oncotarget. 2019 March;10:2270-2281. [Full Text Article]
[PubMed:31040918]
[PMC:PMC6481348]
Related Antibodies: LS-B1825.
3
Human equilibrative nucleoside transporter-1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression; do they have survival impact to pancreatic cancer?. Dae Wook Hwang, Eun Shin, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon. Annals of hepato-biliary-pancreatic surgery. 2020 May;24:127-136. [Full Text Article]
[PubMed:32457256]
[PMC:PMC7271117]
Related Antibodies: LS-C172855.
4
RRM1 Expression as a Prognostic Biomarker for Unresectable or Recurrent Biliary Tract Cancer Treated with Gemcitabine plus Cisplatin. Jung Won Chun, Boyoung Lee, Weon Seo Park, Nayoung Han , Eun Kyung Hong , Eun Young Park, Sung Sik Han, Sang-Jae Park, Tae Hyun Kim, Woo Jin Lee, Sang Myung Woo. Journal of Clinical Medicine. 2021 Oct;10:4652. [Full Text Article]
[PubMed:34682775]
[PMC:PMC8538709]
Related Antibodies: LS-B1825.
5
Establishment and characterization of a new human gallbladder carcinoma cell line. Sekine S, Shimada Y, Nagata T, Moriyama M, Omura T, Yoshioka I, Hori R, Matsui K, Sawada S, Okumura T, Yoshida T, Tsukada K. Anticancer research. 2012 Aug;32:3211-8. [Full Text Article]
[PubMed:22843894]
Related Antibodies: LS-B1825.
6
Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity. Hartford CM, Duan S, Delaney SM, Mi S, Kistner EO, Lamba JK, Huang RS, Dolan ME. Blood. 2009 113:2145-53.
[PubMed:19109566]
[PMC:PMC2652364]
Related Antibodies: LS-C98044.
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PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).