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DBR1

debranching RNA lariats 1

Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.

Gene Name:	debranching RNA lariats 1
Synonyms:	DBR1, Lariat debranching enzyme, RNA lariat debranching enzyme
Target Sequences:	NM_016216 NP_057300.2 Q9UK59

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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