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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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DAPK2 / DAP Kinase 2

death-associated protein kinase 2

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation.Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Gene Name: death-associated protein kinase 2
Family/Subfamily: Protein Kinase , DAPK
Synonyms: DAPK2, DAP-kinase-related protein 1, DRP-1, DRP1, DAP kinase 2
Target Sequences: NM_014326 NP_055141.2 Q9UIK4

Publications (1)

1
Lyn kinase promotes erythroblast expansion and late-stage development. Karur VG, Lowell CA, Besmer P, Agosti V, Wojchowski DM. Blood. 2006 108:1524-32. [PubMed:16705093] [PMC:PMC1895506]


DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 / DRP1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Mouse Monoclonal [clone 1B5] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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Goat Polyclonal to Human DAPK2 / DAP Kinase 2
Rabbit, Mouse, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $425.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $425.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1C5] (IgG3) to Human DAPK2 / DAP Kinase 2
Flo, IF, IHC, IHC-P, WB
Unconjugated
100µl   0.76mg/ml   $345.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded colon tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1C5] (IgG3) to Human DAPK2 / DAP Kinase 2
Dog, Rat, Human, Monkey
Flo, IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg   $395.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1F7] (IgG1) to Human DAPK2 / DAP Kinase 2
IF, IHC, IHC-P, WB
Unconjugated
100µl   0.78mg/ml   $345.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1F7] (IgG1) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg   $395.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1C8] (IgG3) to Human DAPK2 / DAP Kinase 2
Flo, IHC, IHC-P, WB
Unconjugated
100µl   0.72mg/ml   $345.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemical staining of paraffin-embedded lung tissue using anti-DAPK2 mouse monoclonal antibody. (Dilution 1:50).
Select
Mouse Monoclonal [clone OTI1C8] (IgG3) to Human DAPK2 / DAP Kinase 2
Human
Flo, IHC, IP, WB
Unconjugated, Carrier-free
100µg   $395.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 / DRP1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal [clone 1B5] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100µg   $395.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.
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Mouse Monoclonal [clone OTI1B10] (IgG2b) to Human DAPK2 / DAP Kinase 2
Flo, IF, WB
Unconjugated
100µl   0.84mg/ml   $345.00
DAPK2 / DAP Kinase 2 Antibody - Anti-DAPK2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DAPK2.
Select
Mouse Monoclonal [clone OTI1B10] (IgG2b) to Human DAPK2 / DAP Kinase 2
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100µg   $395.00
DAPK2 / DAP Kinase 2 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Flo, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using DAPK2 (Phospho-Ser318) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
DAPK2 / DAP Kinase 2 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
DAPK2 / DAP Kinase 2 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using DAPK2 (Phospho-Ser318) antibody.
Select
Rabbit Polyclonal (IgG) to Human DAPK2 / DAP Kinase 2
Mouse, Human
ELISA, IF, IHC
Unconjugated
100µg   $305.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).