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Unfortunately, the antibody (ID:162829) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



DAB2

Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)

Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domain-containing proteins such as EPS15, EPS15L1 and ITSN1. Involved in endocytosis of cystic fibrosis transmembrane conductance regulator/CFTR. Involved in endocytosis of megalin/LRP2 lipoprotein receptor during embryonal development. Required for recycling of the TGF-beta receptor. Involved in CFTR trafficking to the late endosome. Involved in several receptor-mediated signaling pathways. Involved in TGF-beta receptor signaling and facilitates phosphorylation of the signal transducer SMAD2. Mediates TFG-beta-stimulated JNK activation. May inhibit the canoniocal Wnt/beta-catenin signaling pathway by stabilizing the beta-catenin destruction complex through a competing association with axin preventing its dephosphorylation through protein phosphatase 1 (PP1). Sequesters LRP6 towards clathrin-mediated endocytosis, leading to inhibition of Wnt/beta-catenin signaling. May activate non-canonical Wnt signaling. In cell surface growth factor/Ras signaling pathways proposed to inhibit ERK activation by interrupting the binding of GRB2 to SOS1 and to inhibit SRC by preventing its activating phosphorylation at 'Tyr-419'. Proposed to be involved in modulation of androgen receptor (AR) signaling mediated by SRC activation; seems to compete with AR for interaction with SRC. Plays a role in the CSF-1 signal transduction pathway. Plays a role in cellular differentiation. Involved in cell positioning and formation of visceral endoderm (VE) during embryogenesis and proposed to be required in the VE to respond to Nodal signaling coming from the epiblast. Required for the epithelial to mesenchymal transition, a process necessary for proper embryonic development. May be involved in myeloid cell differentiation and can induce macrophage adhesion and spreading. May act as a tumor suppressor.

Gene Name: Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
Synonyms: DAB2, Disabled homolog 2, DOC-2, DOC2
Target Sequences: NM_001343 NP_001334.2 P98082
Featured Image

Featured DAB2 Antibody

LS-B6461 is a goat polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue. Learn more about our IHC Validation procedure. All LSBio antibodies are 100% guaranteed.


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Target Reactivity Applications Host Isotype Clonality Clone Format Epitope Publications Type
DAB2 Goat Polyclonal Unconjugated Human IHC-P, WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus) IHC-plus™ LS-B6461
Immunohistochemistry Image
Western blot Image
Goat Polyclonal to Human DAB2
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
DAB2 Rabbit Polyclonal Unconjugated Human IHC-P, WB, Flo aa743-770 No Primary Available
Anti-DAB2 Antibody (aa743-770) IHC-plus™ LS-B12091
Immunohistochemistry Image
Western blot Image
Rabbit Polyclonal to Human DAB2
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
DAB2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA No Primary
Anti-DAB2 Antibody LS-C404871
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DAB2
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
DAB2 Rabbit IgG Polyclonal Unconjugated Human, Mouse, Rat IHC, WB, ELISA No Primary
Anti-DAB2 Antibody LS-C401580
Immunohistochemistry Image
Immunohistochemistry Image
Rabbit Polyclonal (IgG) to Human DAB2
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
DAB2 Rabbit Polyclonal Unconjugated Human WB, IP aa275-325 No Primary
Anti-DAB2 Antibody (aa275-325) LS-C286191
Western blot Image
Western blot Image
Rabbit Polyclonal to Human DAB2
Human
Western blot, Immunoprecipitation
Unconjugated
DAB2 Rabbit Polyclonal Unconjugated Mouse WB aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650) LS-C157905
Western blot Image
Rabbit Polyclonal to Mouse DAB2
Mouse
Western blot
Unconjugated
DAB2 Rabbit Polyclonal Unconjugated Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit WB N-Terminus No Primary
Anti-DAB2 Antibody (N-Terminus) LS-C201408
Western blot Image
Rabbit Polyclonal to Human DAB2
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit
Western blot
Unconjugated
DAB2 Mouse IgG2a,k Monoclonal 1C8 Unconjugated Human WB, ELISA No Primary
Anti-DAB2 Antibody (clone 1C8) LS-C197016
Mouse Monoclonal [clone 1C8] (IgG2a,k) to Human DAB2
Human
Western blot, ELISA
Unconjugated
DAB2 Rabbit Polyclonal HRP Conjugated Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit WB N-Terminus No Primary
Anti-DAB2 Antibody (N-Terminus, HRP) LS-C442980
Western blot Image
Rabbit Polyclonal to Human DAB2
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit
Western blot
HRP Conjugated
DAB2 Rabbit Polyclonal FITC Conjugated Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit WB N-Terminus No Primary
Anti-DAB2 Antibody (N-Terminus, FITC) LS-C442979
Western blot Image
Rabbit Polyclonal to Human DAB2
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit
Western blot
FITC Conjugated
DAB2 Rabbit Polyclonal Biotin Conjugated Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit WB N-Terminus No Primary
Anti-DAB2 Antibody (N-Terminus, Biotin) LS-C442978
Western blot Image
Rabbit Polyclonal to Human DAB2
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Pig, Rabbit
Western blot
Biotin Conjugated
DAB2 Rabbit IgG Polyclonal PE Conjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, PE) LS-C225055
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
PE Conjugated
DAB2 Rabbit IgG Polyclonal FITC Conjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, FITC) LS-C225054
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
FITC Conjugated
DAB2 Rabbit IgG Polyclonal Biotin Conjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, Biotin) LS-C225052
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
Biotin Conjugated
DAB2 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, Azide-free, HRP) LS-C225056
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
HRP Conjugated, Azide-free
DAB2 Rabbit IgG Polyclonal Unconjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus) LS-C327162
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
Unconjugated
DAB2 Rabbit IgG Polyclonal Unconjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650) LS-C320733
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
Unconjugated
DAB2 Mouse IgG Polyclonal Unconjugated Human IF, WB No Primary
Anti-DAB2 Antibody LS-C307169
Mouse Polyclonal (IgG) to Human DAB2
Human
Immunofluorescence, Western blot
Unconjugated
DAB2 Rabbit IgG Polyclonal APC Conjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, APC) LS-C225051
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
APC Conjugated
DAB2 Rabbit IgG Polyclonal Biotin Conjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, Biotin) LS-C221983
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
Biotin Conjugated
DAB2 Rabbit IgG Polyclonal APC Conjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, APC) LS-C221982
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
APC Conjugated
DAB2 Rabbit IgG Polyclonal AP Conjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, AP) LS-C221981
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
AP Conjugated
DAB2 Rabbit IgG Polyclonal FITC Conjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, FITC) LS-C221984
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
FITC Conjugated
DAB2 Rabbit IgG Polyclonal AP Conjugated Human WB, ELISA C-Terminus No Primary
Anti-DAB2 Antibody (C-Terminus, AP) LS-C225050
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot, ELISA
AP Conjugated
DAB2 Rabbit IgG Polyclonal PE Conjugated Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, PE) LS-C221986
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
PE Conjugated
DAB2 Rabbit IgG Polyclonal HRP Conjugated, Azide-free Mouse WB, ELISA aa624-650 No Primary
Anti-DAB2 Antibody (aa624-650, Azide-free, HRP) LS-C221985
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot, ELISA
HRP Conjugated, Azide-free
DAB2 Rabbit IgG Polyclonal MaxLight 650 Conjugated Mouse WB No Primary
Anti-DAB2 Antibody (MaxLight 650) LS-C611364
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot
MaxLight 650 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 550 Conjugated Human WB No Primary
Anti-DAB2 Antibody (MaxLight 550) LS-C603668
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot
MaxLight 550 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 650 Conjugated Human WB No Primary
Anti-DAB2 Antibody (MaxLight 650) LS-C623322
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot
MaxLight 650 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 750 Conjugated Human WB No Primary
Anti-DAB2 Antibody (MaxLight 750) LS-C642970
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot
MaxLight 750 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 750 Conjugated Mouse WB No Primary
Anti-DAB2 Antibody (MaxLight 750) LS-C631017
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot
MaxLight 750 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 405 Conjugated Human WB No Primary
Anti-DAB2 Antibody (MaxLight 405) LS-C564363
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot
MaxLight 405 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 405 Conjugated Mouse WB No Primary
Anti-DAB2 Antibody (MaxLight 405) LS-C552412
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot
MaxLight 405 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 490 Conjugated Mouse WB No Primary
Anti-DAB2 Antibody (MaxLight 490) LS-C572061
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot
MaxLight 490 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 550 Conjugated Mouse WB No Primary
Anti-DAB2 Antibody (MaxLight 550) LS-C591715
Rabbit Polyclonal (IgG) to Mouse DAB2
Mouse
Western blot
MaxLight 550 Conjugated
DAB2 Rabbit IgG Polyclonal MaxLight 490 Conjugated Human WB No Primary
Anti-DAB2 Antibody (MaxLight 490) LS-C584015
Rabbit Polyclonal (IgG) to Human DAB2
Human
Western blot
MaxLight 490 Conjugated
Target Corresponding Antibodies
DAB2
DAB2 Antibody Blocking Peptide - LS-E9886
LS-E9886
DAB2
LS-B12091
DAB2
DAB2 Blocking Peptide - LS-E27595
LS-E27595
DAB2
Type Target Reactivity Sample Type
Sandwich DAB2 Human Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Human DAB2 ELISA Kit (Sandwich ELISA) - LS-F11276
 Image
 Image
Quantitative Sandwich ELISA
96-Well Strip Plate
Human
0.156-10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum, Tissue Homogenates, Plasma
Sandwich (Custom) DAB2 Rat
Rat DAB2 ELISA Kit (Sandwich ELISA) (Custom) - LS-F19301
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
Sandwich (Custom) DAB2 Mouse
Mouse DAB2 ELISA Kit (Sandwich ELISA) (Custom) - LS-F19302
 Image
 Image
Sandwich ELISA
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
Type Target Tag Species Source Purified Biological Activity Known Endotoxin Level Animal-Free
Recombinant DAB2 GST Human Wheat
Human DAB2 Recombinant (GST) Protein - LS-G28147
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
110.22 kDa
Recombinant DAB2 GST Human Wheat
Human DAB2 Recombinant (GST) Protein - LS-G28148
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
108.8 kDa

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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