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CYTIP contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.
Gene Name: | cytohesin 1 interacting protein |
Synonyms: | CYTIP, B3-1, CASP, Cbp HE, CYTHIP, Cytohesin binder and regulator, Cytohesin binding protein HE, Cytohesin-binding protein HE, CYBR, Cytohesin-interacting protein, HE, PSCDBP |
Target Sequences: | NM_004288 NP_004279.3 O60759 |
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