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CYSLTR1 / CYSLT1

cysteinyl leukotriene receptor 1

Cysteinyl leukotriene receptor 1, a Chemoattractant Receptor, is detected in spleen, peripheral blood leukocytes, and lung smooth muscle (Lynch et al., 1999). It binds cysteinyl leukotrienes, which are neutrophil chemoattractants with potent proinflammatory action. Leukotrienes mediate many features of bronchial asthma such as edema, bronchial constriction, and hyperreactivity ( Bisgaard et al., 2000). Selective CysLT1 antagonists are used to treat asthma.

Gene Name: cysteinyl leukotriene receptor 1
Family/Subfamily: GPCR , Chemoattractant
Synonyms: CYSLTR1, Cys-LT1 receptor, CysLT(1), Cys-leukotriene-1 receptor, CYSLT1, CYSLT1R, CYSLTR, HG55, LTD4 receptor, HMTMF81, Cysteinyl lt1 receptor
Target Sequences: NM_006639 NP_006630.1 Q9Y271

Publications (1)

1
Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction. Sekioka T, Kadode M, Fujii M, Kawabata K, Abe T, Horiba M, Kohno S, Nabe T. Allergology international : official journal of the Japanese Society of Allergology. 2015 October;64:351-8. (Human) [Full Text Article] [PubMed:26433531] Related Antibodies: LS-A1317.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CYSLTR1 / CYSLT1 (4)
No (4)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
CYSLTR1 / CYSLT1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CYSLTR1 / CYSLT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.4 kDa
20 µg/$150
CYSLTR1 / CYSLT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.4 kDa
100 µg/$494
CYSLTR1 / CYSLT1 Protein - 12.5% SDS-PAGE of human CYSLTR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.9 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).