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CYP4F22 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.
Gene Name: | Cytochrome P450, family 4, subfamily F, polypeptide 22 |
Synonyms: | CYP4F22, Cytochrome P450 4F22, LI3 |
Target Sequences: | Q6NT55 Q6NT55 |
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