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CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants.
Gene Name: | cytochrome P450, family 4, subfamily F, polypeptide 12 |
Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
Synonyms: | CYP4F12, CYPIVF12, Cytochrome P450 4F12, F22329_1 |
Target Sequences: | NM_023944 NP_076433.3 Q9HCS2 |
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