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CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

CYP3A5 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

Gene Name: cytochrome P450, family 3, subfamily A, polypeptide 5
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP3A5, Aryl hydrocarbon hydroxylase, CYPIIIA5, Cytochrome P450 3A5, Cytochrome p450 IIIa5, Cytochrome P450 HLp2, CP35, Cytochrome P450-PCN3, p450PCN3, PCN3
Target Sequences: NM_000777 NP_000768.1 P20815

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CYP3A5 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CYP3A5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
56.9 kDa
20 µg/$150
CYP3A5 Protein - 12.5% SDS-PAGE of human CYP3A5 stained with Coomassie Blue
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Wheat Germ Extract
GST
80.96 kDa
2 µg/$439
CYP3A5 Protein - Purified recombinant protein CYP3A5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
56.9 kDa
20 µg/$1,107
CYP3A5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
56.9 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).