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CYP27 / CYP27A1

cytochrome P450, family 27, subfamily A, polypeptide 1

CYP27 / CYP27A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Gene Name: cytochrome P450, family 27, subfamily A, polypeptide 1
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP27A1, Cytochrome P450 27, CTX, Cytochrome P-450C27/25, CP27, Vitamin D(3) 25-hydroxylase, CYP27, Sterol 27-hydroxylase
Target Sequences: NM_000784 AAA52142.1 Q02318

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CYP27 / CYP27A1 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CYP27 / CYP27A1 Protein - Purified recombinant protein CYP27A1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
56.9 kDa
20 µg/$1,107
CYP27 / CYP27A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
60.26 kDa
100 µg/$494
CYP27 / CYP27A1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
60.26 kDa
20 µg/$150
CYP27 / CYP27A1 Protein - 12.5% SDS-PAGE of human CYP27A1 stained with Coomassie Blue
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Wheat Germ Extract
GST
86.6 kDa
2 µg/$439
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).