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Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
| Gene Name: | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| Family/Subfamily: | Cytochrome P450 , not assigned-Cytochrome P450 |
| Synonyms: | CYP1A1, AHH, Aryl hydrocarbon hydroxylase, Cytochrome P450-C, CP11, CYPIA1, Cytochrome P450 form 6, Cytochrome p450 ia1, Cytochrome P450 1A1, Cytochrome P450-P1, p1-450, p450-C, p450DX, CYP1 |
| Target Sequences: | NM_000499 NP_000490.1 P04798 |
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