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CYB5R2 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants.
Gene Name: | cytochrome b5 reductase 2 |
Synonyms: | CYB5R2, B5R.2, Cytochrome b5 reductase 2, NADH-cytochrome b5 reductase 2, Cytochrome b5 reductase b5R.2 |
Target Sequences: | NM_016229 NP_057313.2 Q6BCY4 |
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