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Infectious Disease
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2 Shaker Rd Suites
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Lynnwood, WA 98036
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Fax: +1 (206) 577-4565
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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CXCL5
chemokine (C-X-C motif) ligand 5
CXCL5 is a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.
| Gene Name: | chemokine (C-X-C motif) ligand 5 |
| Family/Subfamily: | Intercrine , Intercrine alpha |
| Synonyms: | CXCL5, C-X-C motif chemokine 5, ENA-78(1-78), GCP-2, ENA78, SCYB5, ENA-78, Small inducible cytokine B5, Small-inducible cytokine B5, LIX, AMCF-II |
| Target Sequences: | NM_002994 NP_002985.1 P42830 |
Publications (4)
1
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. Balamayoora Theivanthiran, Kathy S Evans, Nicholas C DeVito, Michael Plebanek, Michael Sturdivant, Luke P Wachsmuth, April Ks Salama, Yubin Kang, David Hsu, Justin M Balko, Douglas B Johnson, Mark Starr, Andrew B Nixon, Alisha Holtzhausen, Brent A Hanks. The Journal of clinical investigation. 2020 May;130:2570-2586. [Full Text Article]
[PubMed:32017708]
[PMC:PMC7190922]
Related Antibodies: LS-C293780.
2
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils. Karim Mahiddine, Adam Blaisdell, Stephany Ma, Amandine Créquer-Grandhomme, Clifford A Lowell, Adrian Erlebacher. The Journal of clinical investigation. 2020 Jan;130:389-403. [Full Text Article]
[PubMed:31600172]
[PMC:PMC6934192]
Related Antibodies: LS-C212192.
3
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy. Nicholas C DeVito, Michael Sturdivant, Balamayooran Thievanthiran, Christine Xiao, Michael P Plebanek, April K S Salama, Georgia M Beasley, Alisha Holtzhausen, Veronica Novotny-Diermayr, John H Strickler, Brent A Hanks. Cell reports. 2021 May;35:109071. [Full Text Article]
[PubMed:33951424]
[PMC:PMC8148423]
Related Antibodies: LS-C104413.
☰ Filters
Products
Proteins
(30)
Type
Over-Expression Lysate
(2)
Recombinant
(28)
Target
CXCL5
(30)
Publications
No
(30)
Tag
6His, N-terminus
(1)
GST
(1)
His-GST
(2)
His-T7
(3)
Myc-DDK (Flag)
(3)
Myc-DDK (Flag), C-terminus
(3)
Species
Human
(19)
Mouse
(8)
Rat
(2)
Source
293T Cells
(1)
CHO Cells
(1)
E. coli
(22)
HEK 293 Cells
(5)
Wheat Germ Extract
(1)
Purification
Purified
(12)
Low Endotoxin Level
Low endotoxin level
(12)
Biologically Active
Biologically active
(14)
E. coli
None
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 7.98 kD. The DTT-reduced protein and non-reduced protein migrates at approximately 10 kD by SDS-PAGE. The N-terminal amino acid is Val.
10 µg/$306; 25 µg/$383
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 78 amino acid recombinant protein has a predicted molecular mass of approximately 8.35 kD. The DTT-reduced and non-reduced protein migrate at approximately 10 kD by SDS-PAGE. The N-terminal amino acid is Ala.
100 µg/$398
HEK 293 Cells
Myc-DDK (Flag), C-terminus
8.3 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag), C-terminus
8.3 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag), C-terminus
8.3 kDa
20 µg/$1,107
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
9.8 kDa
1 mg/$2,948; 20 µg/$377
Wheat Germ Extract
GST
38.28 kDa
10 µg/$479; 25 µg/$670
E. coli
His-T7
13.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
8 kDa (SDS-PAGE)
50 µg/$359; 10 µg/$273
HEK 293 Cells
Myc-DDK (Flag)
8.3 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
11.97 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
11.97 kDa
100 µg/$494
E. coli
None
Biologically active
7.8 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
9.8 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
7.6 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
10.1 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.0 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.8 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~11 kDa
20 µg/$291; 200 µg/$908; 1 mg/$2,851
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~11 kDa
20 µg/$432; 1 mg/$4,915
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
7.95 kDa
50 µg/$487; 10 µg/$303; 1 mg/$2,837; 500 µg/$1,987
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.0 kDa
20 µg/$360; 100 µg/$728
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
7.95kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
E. coli
6His, N-terminus
11 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
Viewing 1-25
of 30
product results
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