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CXCL16

chemokine (C-X-C motif) ligand 16

Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis By similarity. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Gene Name: chemokine (C-X-C motif) ligand 16
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL16, C-X-C motif chemokine 16, SCYB16, Transmembrane chemokine CXCL16, CXC chemokine ligand 16, CXCLG16, Small-inducible cytokine B16, SR-PSOX, SRPSOX
Target Sequences: NM_022059 NP_071342.2 Q9H2A7

Publications (1)

1
Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy. Ahmed M Abu El-Asrar , Mohd Imtiaz Nawaz, Ajmal Ahmad, Alexandra De Zutter, Mohammad Mairaj Siddiquei, Marfa Blanter, Eef Allegaert, Priscilla W Gikandi, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf. Frontiers in immunology. 2021 Jan;11:601639. [Full Text Article] [PubMed:33552057] [PMC:PMC7854927] Related Antibodies: LS-B8223.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).