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CXCL11

chemokine (C-X-C motif) ligand 11

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: chemokine (C-X-C motif) ligand 11
Family/Subfamily: Intercrine , Intercrine alpha
Synonyms: CXCL11, Beta-R1, Chemokine h174, Chemokine ip-9, Chemokine itac, H174, I-TAC, IP9, ITAC, IP-9, SCYB11, Small inducible cytokine B11, B-R1, C-X-C motif chemokine 11, SCYB9B, Small-inducible cytokine B11
Target Sequences: NM_005409 NP_005400.1 O14625

Publications (1)

1
A gene expression profile related to immune dampening in the tumor microenvironment is associated with poor prognosis in gastric adenocarcinoma. Pasini FS, Zilberstein B, Snitcovsky I, Roela RA, Mangone FR, Ribeiro U Jr, Nonogaki S, Brito GC, Callegari GD, Cecconello I, Alves VA, Eluf-Neto J, Chammas R, Federico MH. Journal of gastroenterology. 2014 49:1453-66. (IHC; Human) [Full Text Article] [PubMed:24217965] [PMC:PMC4223540]

☰ Filters
Products
Proteins (18)
Recombinant (18)
CXCL11 (18)
No (18)
Fc, C-terminus (2)
GST (1)
His (3)
His-GST (2)
His-T7 (2)
Bovine (1)
Human (11)
Mouse (5)
Rat (1)
E. coli (15)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (8)
Low endotoxin level (6)
Biologically active (8)
CXCL11 Protein - Recombinant  Interferon Inducible T-Cell Alpha Chemoattractant By SDS-PAGE
Select
E. coli
His-GST
39 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CXCL11 Protein - Recombinant Interferon Inducible T-Cell Alpha Chemoattractant By SDS-PAGE
Select
E. coli
His-T7
12.1 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
Select
E. coli
None
Biologically active
8.3 kDa
20 µg/$370; 5 µg/$282
CXCL11 Protein - Human CXCL11 chemoattracts Baf3-mCXCR3 transfectants in a dose dependent manner. The ED50 = 1-5 ng/mL.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 8.3 kD. The DTT-reduced protein migrates at approximately 11 kD and non-reduced protein migrates at approximately 13 kD by SDS-PAGE. The N-terminal amino acid is Methion
10 µg/$294; 25 µg/$359; 100 µg/$720; 500 µg/$1,779
CXCL11 Protein - CXCR3 transfected BaF3 cells chemoattracted by mCXCL11.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 80 amino acid recombinant protein has a predicted molecular mass of approximately 9.2 kD. The DTT-reduced protein migrates at approximately 11 kD and non-reduced protein migrates at approximately 13 kD by SDS-PAGE. The N-terminal amino acid is Methion
10 µg/$306; 25 µg/$420; 100 µg/$907
CXCL11 Protein
Select
HEK 293 Cells
Fc, C-terminus
35 kDa
20 µg/$1,107
CXCL11 Protein
Select
HEK 293 Cells
Fc, C-terminus
35 kDa
20 µg/$1,107
CXCL11 Protein - 12.5% SDS-PAGE of human CXCL11 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
36.08 kDa
2 µg/$439
CXCL11 Protein
Select
E. coli
His
13 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CXCL11 Protein - Recombinant Interferon Inducible T-Cell Alpha Chemoattractant By SDS-PAGE
Select
E. coli
His
12.5 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
CXCL11 Protein
Select
E. coli
None
Biologically active
8.3 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CXCL11 Protein
Select
E. coli
None
Biologically active
9.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.3 kDa
5 µg/$268; 20 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
9.0 kDa
5 µg/$268; 20 µg/$349
CXCL11 Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$559; 1 mg/$2,551
CXCL11 Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
CXCL11 Protein - Recombinant Interferon Inducible T-Cell Alpha Chemoattractant By SDS-PAGE
Select
E. coli
His-GST
40.7 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CXCL11 Protein - Recombinant Interferon Inducible T-Cell Alpha Chemoattractant By SDS-PAGE
Select
E. coli
His-T7
12.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).