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CX3CL1 / Fractalkine

chemokine (C-X3-C motif) ligand 1

CX3CL1/fractalkine is a chemokine with a unique CX3C motif. Fractalkine is synthesized in endothelial cells as a membrane protein, and the N-terminal domain containing a CX3C motif is cleaved and secreted. Fractalkine is the first described cell-surface anchored chemokine and has potent mononuclear cell-directed adhesion and chemotactic properties. Fractalkine is involved in the pathogenesis of various chronic inflammatory diseases, such as rheumatoid arthritis and atherosclerosis.

Gene Name: chemokine (C-X3-C motif) ligand 1
Family/Subfamily: Intercrine , Intercrine delta
Synonyms: CX3CL1, ABCD-3, C-X3-C motif chemokine 1, C3Xkine, Chemokine ntt, CXC3C, FKN, Fractalkine, Neurotactin, CXC3, NTN, SCYD1, Small-inducible cytokine D1
Target Sequences: NM_002996 NP_002987.1 P78423

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).