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CTSZ / Cathepsin Z is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
Gene Name: | cathepsin Z |
Family/Subfamily: | Protease , Cysteine C1 |
Synonyms: | CTSZ, Cathepsin IV, Cathepsin P, Cathepsin Z1, Carboxypeptidase LB, Cathepsin X, Cathepsin Y, CTSX, Lysosomal carboxypeptidase B, Preprocathepsin P, Cathepsin B2, Cathepsin Z, Cysteine-type carboxypeptidase |
Target Sequences: | NM_001336 NP_001327.2 Q9UBR2 |
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