CTLA4 / CD152

cytotoxic T-lymphocyte-associated protein 4

CTLA4 / CD152 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

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Products

Proteins (51)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (45)

Target

CTLA4 / CD152 (51)

Publications

No (51)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, C-terminus (7)

6His, N-terminus (2)

DDK (Flag)-His, C-terminus (1)

DDK,C-terminus (2)

Fc (1)

Fc, C-terminus (5)

Fc-AVI, C-terminus (1)

Fc-His, C-terminus (1)

Flag,C-terminus (2)

GST, C-terminus (2)

GST, N-terminus (1)

His (4)

His, N-Terminal (2)

His,C-terminus (3)

His-T7 (3)

Human IgG1 Fc (1)

Human Mutant IgG1 Fc (1)

mFc, C-terminus (1)

Mouse IgG2 Fc (2)

Mouse Mutant IgG2a Fc (1)

Myc-DDK (Flag) (4)

more less

Species

Crab-eating macaque (2)

Guinea pig (3)

Human (28)

Mouse (14)

Rat (2)

Source

293T Cells (2)

CHO Cells (6)

E. coli (6)

HEK 293 Cells (7)

Human (1)

Human Cells (10)

Mammalian Cells (13)

NS1 Cells (2)

Pichia pastoris (1)

Wheat Germ Extract (1)

Yeast (2)

more less

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (33)

Biologically Active

Biologically active (7)

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Human CTLA4 / CD152 Protein (Recombinant 6His, C-terminus) (Lys36-Asp161) - LS-G40272

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.3kD

Price:

10 µg/$248; 50 µg/$299; 500 µg/$887; 1 mg/$1,203

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Mouse CTLA4 / CD152 Protein (Recombinant 6His, C-terminus) (Ala37-Asp161) - LS-G40273

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.6kD

Price:

10 µg/$248; 50 µg/$299; 500 µg/$887; 1 mg/$1,203

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Mouse CTLA4 / CD152 Protein (Recombinant Fc, C-terminus) (Ala37-Asp161) - LS-G40339

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

40.4kD

Price:

10 µg/$248; 50 µg/$277; 500 µg/$725; 1 mg/$1,113

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Guinea pig CTLA4 / CD152 Protein (Recombinant 6His, C-terminus) - LS-G136752

Source:

Yeast

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.1 kDa

Price:

50 µg/$453; 10 µg/$303; 1 mg/$2,064; 500 µg/$1,538

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Human CTLA4 / CD152 Protein (Recombinant) - LS-G133812

Source:

CHO Cells

Tag:

None

Molecular Weight:

78.7 kDa or 45-50 kDa or 80-90 kDa

Price:

200 µg/$349; 50 µg/$268

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CTLA4 / CD152 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116101

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.66 kDa

Price:

100 µg/$494

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Guinea pig CTLA4 / CD152 Protein (Recombinant His,C-terminus) (Ala37-Asp161) - LS-G139429

Source:

Pichia pastoris

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.1 kDa

Price:

10 µg/$368; 50 µg/$479

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Human CTLA4 / CD152 Protein (Recombinant Fc-His, C-terminus) - LS-G142253

Source:

HEK 293 Cells

Tag:

Fc-His, C-terminus

Molecular Weight:

40 kDa

Price:

20 µg/$1,107

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Human CTLA4 / CD152 Protein (Recombinant DDK (Flag)-His, C-terminus) - LS-G142258

Source:

HEK 293 Cells

Tag:

DDK (Flag)-His, C-terminus

Molecular Weight:

16 kDa

Price:

20 µg/$1,107

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CTLA4 / CD152 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120524

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.15 kDa

Price:

100 µg/$494

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Human CTLA4 / CD152 Protein (Recombinant His) - LS-G2180

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CTLA4 / CD152 Protein (Over-Expression Lysate 6His, N-terminus) (Lys36-Asp161) - LS-G26771

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

19 kDa

Price:

100 µg/$298

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Human CTLA4 / CD152 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Lys36-Asp161) - LS-G26902

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

19 kDa

Price:

200 µl/$283

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Human CTLA4 / CD152 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75445

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.15 kDa

Price:

20 µg/$150

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Human CTLA4 / CD152 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75447

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.66 kDa

Price:

20 µg/$150

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Mouse CTLA4 / CD152 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa36-161) - LS-G56189

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human CTLA4 / CD152 Protein (Recombinant GST, N-terminus) (aa36-135) - LS-G58254

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse CTLA4 / CD152 Protein (Recombinant His) (Met1-Phe162) - LS-G98119

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.3 kDa

Price:

100 µg/$413

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Human CTLA4 / CD152 Protein (Recombinant Human Mutant IgG1 Fc) (aa37-160) - LS-G4085

Source:

CHO Cells

Tag:

Human Mutant IgG1 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

500 µg/$428; 100 µg/$288

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Mouse CTLA4 / CD152 Protein (Recombinant Mouse IgG2 Fc) (aa38-160) - LS-G4116

Source:

NS1 Cells

Tag:

Mouse IgG2 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

500 µg/$428; 100 µg/$288

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Human CTLA4 / CD152 Protein (Recombinant Mouse IgG2 Fc) (aa37-160) - LS-G4067

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$337

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Human CTLA4 / CD152 Protein (Recombinant Human IgG1 Fc) (aa37-160) - LS-G4034

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

500 µg/$400; 100 µg/$281

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Mouse CTLA4 / CD152 Protein (Recombinant Mouse Mutant IgG2a Fc) (aa1-160) - LS-G4147

Source:

NS1 Cells

Tag:

Mouse Mutant IgG2a Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

500 µg/$428; 100 µg/$288

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Human CTLA4 / CD152 Protein (Recombinant 6His, C-terminus) - LS-G136764

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.3 kDa

Price:

50 µg/$327; 10 µg/$259; 1 mg/$1,470; 500 µg/$1,129

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Mouse CTLA4 / CD152 Protein (Recombinant 6His, C-terminus) - LS-G136773

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14.6 kDa

Price:

50 µg/$327; 10 µg/$259; 1 mg/$1,470; 500 µg/$1,129

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