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CTGF

connective tissue growth factor

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Gene Name: connective tissue growth factor
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: CTGF, CCN family member 2, CCN2, IGFBP8, IGF-binding protein 8, NOV2, HCS24, IBP-8, IGFBP-8
Target Sequences: NM_001901 NP_001892.1 P29279

Publications (5)

1
A physiological role for connective tissue growth factor in early wound healing. Alfaro MP, Deskins DL, Wallus M, DasGupta J, Davidson JM, Nanney LB, A Guney M, Gannon M, Young PP. Laboratory investigation; a journal of technical methods and pathology. 2013 93:81-95. (ICC, IHC; Mouse) [PubMed:23212098]
2
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human) [Full Text Article] [PubMed:29854742] [PMC:PMC5944282]
3
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Jack Leslie, Marina García Macia, Saimir Luli, Julie C Worrell, William J Reilly, Hannah L Paish, Amber Knox, Ben S Barksby, Lucy M Gee, Marco Y W Zaki, Amy L Collins, Rachel A Burgoyne, Rainie Cameron, Charlotte Bragg, Xin Xu, Git W Chung, Colin D A Brown, Andrew D Blanchard, Carmel B Nanthakumar, Morten Karsdal, Stuart M Robinson, Derek M Manas, Gourab Sen, Jeremy French, Steven A White, Sandra Murphy, Matthias Trost, Johannes L Zakrzewski, Ulf Klein, Robert F Schwabe, Ingmar Mederacke, Colin. Nature metabolism. 2020 November;2:1350-1367. [Full Text Article] [PubMed:33168981] [PMC:PMC7116435]
4
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797]
5
Calcineurin (PPP3CB) regulates angiotensin II-dependent vascular remodelling by potentiating EGFR signalling in mice. Alexander Nolze, Conny Köhler, Stefanie Ruhs, Katja Quarch, Nicole Strätz, Michael Gekle, Claudia Grossmann. Acta physiologica (Oxford, England). 2021 November;233:e13715. [Full Text Article] [PubMed:34228904]
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Antibodies (170)
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CTGF Antibody - Anti-CTGF antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CTGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
CTGF Antibody
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CTGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
CTGF ELISA Kit
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Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CTGF ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
CTGF Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
37.7 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
CTGF ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
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E. coli
His, N-Terminal
14.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CTGF ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CTGF ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
CTGF ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CTGF ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$929
CTGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CTGF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$685
CTGF ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
CTGF ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
63 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$414
CTGF Antibody - Western blot of recombinant CTGF.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CTGF Mouse anti-Human Monoclonal (aa248-349) Antibody
Human
WB
Unconjugated
100 µl/$295; 200 µl/$331; 500 µl/$451; 1 ml/$511; 2 ml/$648; 5 ml/$1,099
CTGF Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CTGF Goat anti-Human Polyclonal (Amino Acids 111-123) Antibody
Mouse, Human
IF, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$460
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CTGF Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
CTGF Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using CTGF Polyclonal Antibody at dilution of 1:50.
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CTGF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CTGF Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CTGF antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CTGF Rabbit anti-Human Polyclonal (aa315-349) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
CTGF Antibody - IHC of CTGF antibody. Frozen section of human umbilical cord.
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CTGF Mouse Monoclonal (2154-60) Antibody
Rat, Human
IHC, IHC-Fr, IHC-P
Unconjugated
500 µg/$850
CTGF Antibody - Immunohistochemistry of paraffin-embedded rat heart using CTGF antibody at dilution of 1:100 (40x lens).
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CTGF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CTGF Protein - Recombinant Connective Tissue Growth Factor By SDS-PAGE
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E. coli
His
13.2 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CTGF Antibody - CTGF antibody IHC-paraffin. IHC(P): Human Mammary Cancer Tissue.
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CTGF Rabbit anti-Human Polyclonal (aa58-349) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CTGF Antibody - CTGF monoclonal antibody (M01), clone 2C11. Western Blot analysis of CTGF expression in human liver.
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CTGF Mouse anti-Human Monoclonal (2C11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Viewing 1-25 of 233 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).