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CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CSTF3 is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Gene Name: | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| Synonyms: | CSTF3, CSTF 77 kDa subunit, CF-1 77 kDa subunit, CSTF-77 |
| Target Sequences: | NM_001326 NP_001317.1 Q12996 |
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