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CSNK1G2 / CKI-Gamma 2

casein kinase 1, gamma 2

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.

Gene Name: casein kinase 1, gamma 2
Family/Subfamily: Protein Kinase , Casein kinase I
Synonyms: CSNK1G2, Casein kinase 1, gamma 2, Casein kinase I gamma 2, CKI Gamma 2, CKI-gamma 2, CK1 gamma 2, CK1g2, Casein Kinase 1 gamma 2
Target Sequences: NM_001319 NP_001310.3 P78368

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Products
Antibodies (57)
Primary (57)
CSNK1G2 / CKI-Gamma 2 (57)
Human (57)
Mouse (23)
Rat (10)
Bovine (4)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (6)
Pig (3)
Xenopus (3)
IHC (18)
IHC-P (8)
WB (55)
ELISA (18)
ICC (1)
IF (5)
IP (1)
Peptide-ELISA (2)
rabbit (32)
mouse (25)
Product Group
IHCPlus (1)
IgG (24)
IgG1 (8)
IgG2a (10)
IgG2a,k (6)
IgG2b,k (1)
monoclonal mc (25)
polyclonal pc (32)
3F4 (1)
OTI1A9 (2)
OTI1D12 (2)
OTI1E9 (2)
OTI1H6 (2)
OTI2F2 (2)
OTI2F3 (2)
OTI3G4 (2)
OTI4H3 (2)
OTI5F4 (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (5)
Carrier-free (9)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Preservative Free (1)
Unconjugated (36)
aa163-415 (18)
aa329-360 (7)
C-Terminus (4)
aa130-179 (4)
10-90 aa, N-terminal (1)
Gly7 (1)
N-Terminus (1)
aa10-59 (1)
aa315-415 (1)
No (57)
CSNK1G2 / CKI-Gamma 2 Antibody - Immunofluorescence analysis of A549 cells.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CSNK1G2 / CKI-Gamma 2 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer at dilution 1:100
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
CSNK1G2 / CKI-Gamma 2 Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CSNK1G2 / CKI-Gamma 2 Antibody - Western blot of Casein Kinase Igamma2 antibody
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CSNK1G2 / CKI-Gamma 2 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
CSNK1G2 / CKI-Gamma 2 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CSNK1G2 / CKI-Gamma 2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CSNK1G2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa163-415) (OTI4H3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
CSNK1G2 / CKI-Gamma 2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CSNK1G2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa163-415) (Carrier-free) (OTI4H3) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
CSNK1G2 / CKI-Gamma 2 Antibody - Western blot of Casein Kinase I2 (G7) pAb in extracts from HeLa cells.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (Gly7) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
CSNK1G2 / CKI-Gamma 2 Antibody - Immunofluorescent analysis of CK1 gamma 2 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CSNK1G2 / CKI-Gamma 2 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CK1g2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal (aa329-360) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (aa315-415) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
CSNK1G2 / CKI-Gamma 2 Antibody - Detection limit for recombinant GST tagged CSNK1G2 is 3 ng/ml as a capture antibody.
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CSNK1G2 / CKI-Gamma 2 Mouse anti-Human Monoclonal (3F4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CSNK1G2 / CKI-Gamma 2 Antibody - Western blot analysis of extracts from HeLa cells and 293 cells, using CKI-?2 antibody.
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CSNK1G2 / CKI-Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Viewing 1-25 of 57 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).