LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Unfortunately, the antibody (ID:151565) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



CSF1R / CD115 / FMS

colony stimulating factor 1 receptor

Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration, and promotes cancer cell invasion. Activates several signaling pathways in response to ligand binding. Phosphorylates PIK3R1, PLCG2, GRB2, SLA2 and CBL. Activation of PLCG2 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, that then lead to the activation of protein kinase C family members, especially PRKCD. Phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leads to activation of the AKT1 signaling pathway. Activated CSF1R also mediates activation of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, and of the SRC family kinases SRC, FYN and YES1. Activated CSF1R transmits signals both via proteins that directly interact with phosphorylated tyrosine residues in its intracellular domain, or via adapter proteins, such as GRB2. Promotes activation of STAT family members STAT3, STAT5A and/or STAT5B. Promotes tyrosine phosphorylation of SHC1 and INPP5D/SHIP-1. Receptor signaling is down-regulated by protein phosphatases, such as INPP5D/SHIP-1, that dephosphorylate the receptor and its downstream effectors, and by rapid internalization of the activated receptor.

Gene Name: colony stimulating factor 1 receptor
Family/Subfamily: Protein Kinase , PDGF Receptor
Synonyms: CSF1R, CD115 antigen, CSF-1R, CSF-1-R, CSF-1 receptor, FMS, Fim-2, FIM2, FMS proto-oncogene, M-CSFR, HDLS, M-cfs receptor, C-FMS, CD115, CSF1 receptor, CSFR, M-CSF-R, MCSF Receptor, Proto-oncogene c-Fms
Target Sequences: NM_005211 NP_005202.2 P07333

Filtered By: None
Target
csf1r-cd115-fms (131)
Reactivity
Human (92)
Mouse (63)
Rat (38)
Avian (6)
Bat (2)
Bovine (4)
Cat (4)
Chicken (2)
Dog (3)
Hamster (1)
Horse (3)
Monkey (3)
Pig (2)
Sheep (2)
Zebrafish (2)
Application
IHC (35)
IHC-Fr (1)
IHC-P (18)
WB (92)
Flo (24)
ELISA (71)
Func (1)
ICC (10)
IF (21)
IP (1)
Neut (6)
Host
rabbit (99)
mouse (10)
goat (2)
rat (18)
sheep (2)
Isotype
IgG (71)
IgG1 (6)
IgG1,k (8)
IgG2a,k (4)
IgG2b (5)
Clonality
monoclonal mc (29)
polyclonal pc (102)
Clone
12-3A3-1B10 (2)
1486CT328.53.37 (1)
1G4 (1)
460615 (1)
604B5 2E11 (3)
6B9B9 (1)
6B9H2 (1)
AFS98 (4)
SP211 (1)
Format
AP Conjugated (4)
APC Conjugated (7)
Azide-free (4)
Biotin Conjugated (11)
FITC Conjugated (9)
HRP Conjugated (6)
PE Conjugated (6)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (86)
Epitope
C-Terminus (10)
pTyr809 (8)
aa895-923 (7)
pTyr723 (5)
Extracellular Domain (3)
aa20-511 (3)
aa639-868 (3)
aa734-900 (3)
aa768-928 (3)
pTyr561 (3)
pTyr699 (3)
pTyr708 (3)
aa344-497 (2)
aa750-830 (2)
aa781-830 (2)
Asn805 (1)
Gln718 (1)
Glu557 (1)
Ile803 (1)
Internal (1)
aa500-580 (1)
aa531-580 (1)
aa640-720 (1)
aa660-740 (1)
aa669-718 (1)
aa691-740 (1)
aa700-710 (1)
aa734-744 (1)
aa894-923 (1)
aa910-940 (1)
aa940-971 (1)
aa955-972 (1)
Publications
No (128)
Yes (3)
Showing 1-25 out of 131 results
Anti-CSF1R / CD115 / FMS Antibody (phospho-Tyr723) IHC-plus™ LS-B1070

Rabbit Polyclonal to Human CSF1R / CD115 / FMS
Mouse, Rat, Human
IHC-P
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (clone SP211) LS-C210434

Rabbit Monoclonal [clone SP211] (IgG) to Human CSF1R / CD115 / FMS
Human
IHC-P
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa344-497, clone 6B9H2) LS-C285887

Mouse Monoclonal [clone 6B9H2] (IgG2b) to Human CSF1R / CD115 / FMS
Human
ELISA Flo IHC-P WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa895-923) LS-C164350

Rabbit Polyclonal to Mouse CSF1R / CD115 / FMS
Mouse, Human
ELISA IHC-P WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (Extracellular Domain) LS-C6868

Rabbit Polyclonal (IgG) to Mouse CSF1R / CD115 / FMS
Mouse
Flo ICC IP WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (clone AFS98) LS-C106370

Rat Monoclonal [clone AFS98] (IgG2a,k) to Mouse CSF1R / CD115 / FMS
Mouse
Flo IHC-Fr WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa691-740) LS-C117756

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa531-580) LS-C117866

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Human
ELISA IF IHC-P
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (phospho-Tyr723) LS-C8599

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Mouse, Human
ELISA WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa344-497, clone 6B9B9) LS-C285882

Mouse Monoclonal [clone 6B9B9] (IgG2b) to Human CSF1R / CD115 / FMS
Human
ELISA ICC IHC-P WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (Extracellular Domain, APC) LS-C130595

Mouse Monoclonal (IgG1) to Human CSF1R / CD115 / FMS
Human
Flo
APC Conjugated
Anti-CSF1R / CD115 / FMS Antibody (Extracellular Domain) LS-C37255

Sheep Polyclonal (IgG) to Mouse CSF1R / CD115 / FMS
Mouse
ELISA IHC WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (clone 1G4) LS-C196979

Mouse Monoclonal [clone 1G4] (IgG1,k) to Human CSF1R / CD115 / FMS
Human
ELISA WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa700-710) LS-C139625

Goat Polyclonal to Human CSF1R / CD115 / FMS
Mouse, Dog, Rat, Hamster, Horse, Bat, Human, Monkey
ELISA WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa20-511, APC) LS-C130596

Rat Monoclonal (IgG2b) to Mouse CSF1R / CD115 / FMS
Mouse
Flo
APC Conjugated
Anti-CSF1R / CD115 / FMS Antibody (clone AFS98, Biotin) LS-C106480

Rat Monoclonal [clone AFS98] (IgG2a,k) to Mouse CSF1R / CD115 / FMS
Mouse
Flo
Biotin Conjugated
Anti-CSF1R / CD115 / FMS Antibody (phospho-Tyr809) LS-C5829

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Mouse, Human
WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (FITC) LS-C255501

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Human
ELISA Flo ICC IF WB
FITC Conjugated
Anti-CSF1R / CD115 / FMS Antibody LS-C167079

Rabbit Polyclonal to Human CSF1R / CD115 / FMS
Human
Flo IF WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (phospho-Tyr723) LS-C381291

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (phospho-Tyr723) LS-C199235

Rabbit Polyclonal (IgG) to Human CSF1R / CD115 / FMS
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa734-744) LS-C139626

Goat Polyclonal to Human CSF1R / CD115 / FMS
Dog, Bovine, Pig, Horse, Human
ELISA WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (aa734-900) LS-C293464

Rabbit Polyclonal (IgG) to Rat CSF1R / CD115 / FMS
Rat
ELISA WB
Unconjugated
Anti-CSF1R / CD115 / FMS Antibody (clone 604B5 2E11, RPE) LS-C188196

Rat Monoclonal [clone 604B5 2E11] (IgG1) to Mouse CSF1R / CD115 / FMS
Mouse, Rat
Flo
RPE Conjugated
Anti-CSF1R / CD115 / FMS Antibody LS-C167080

Mouse Monoclonal to Human CSF1R / CD115 / FMS
Human
WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number