CS1 / CLSTN1

calsyntenin 1

Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals.

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Products

ELISA Kits (2)

Type

Custom (1)

Sandwich (1)

Target

CS1 / CLSTN1 (2)

Reactivity

Human (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

Publications

No (2)

Sample Type

Plasma (1)

Serum (1)

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Human CS1 / CLSTN1 (Sandwich ELISA) ELISA Kit - LS-F38084

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human CS1 / CLSTN1 (Custom ELISA) ELISA Kit - LS-F50171

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$823

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