CRYGB

crystallin, gamma B

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CRYGB (5)

Publications

No (5)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Rat (1)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human CRYGB Protein (Recombinant GST, N-terminus) (aa76-175) - LS-G58224

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CRYGB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65696

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

20 µg/$1,107

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Rat CRYGB Protein (Recombinant 6His, N-terminus) (aa2-175) - LS-G57150

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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CRYGB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116110

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

100 µg/$494

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Human CRYGB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76056

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.7 kDa

Price:

20 µg/$150

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