Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CRY1

cryptochrome circadian clock 1

CRY1 / Cryptochrome circadian clock 1 encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

Gene Name: cryptochrome circadian clock 1
Synonyms: CRY1, Chryptochrome 1, Cryptochrome-1, Photolyase homolog 1, PHLL1
Target Sequences: NM_004075 NP_004066.1 Q16526

Publications (1)

1
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair10<sup> Department of Urology, Medical Oncology and Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA. karen.knudsen@jefferson.edu. Ayesha A Shafi, Chris M McNair , Jennifer J McCann , Mohammed Alshalalfa, Anton Shostak, Tesa M Severson, Yanyun Zhu, Andre Bergman, Nicolas Gordon, Amy C Mandigo, Saswati N Chand, Peter Gallagher, Emanuela Dylgjeri, Talya S Laufer, Irina A Vasilevskaya, Matthew J Schiewer , Michael Brunner, Felix Y Feng, Wilbert Zwart, Karen E Knudsen. Nature communications. 2021 Jan;12:401. [Full Text Article] [PubMed:33452241] [PMC:PMC7810852] Related Antibodies: LS-B6955.

☰ Filters
Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
CRY1 (5)
No (5)
GST (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
CRY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
66.2 kDa
100 µg/$494
CRY1 Protein - Recombinant Cryptochrome 1 By SDS-PAGE
Select
E. coli
His-GST
45.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CRY1 Protein - 12.5% SDS-PAGE of human CRY1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
90.2 kDa
2 µg/$439
CRY1 Protein - Purified recombinant protein CRY1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
66.2 kDa
20 µg/$1,107
CRY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
66.2 kDa
20 µg/$150
Viewing 1-5 of 5 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).