CRTC1 / MECT1 / TORC1

CREB regulated transcription coactivator 1

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

CRTC1 / MECT1 / TORC1 (8)

Publications

No (8)

Tag

GST, N-terminus (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

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Human CRTC1 / MECT1 / TORC1 Protein (Recombinant His-T7, N-terminus) (Met1-Ser172) - LS-G133315

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

22.9kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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CRTC1 / MECT1 / TORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113288

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.1 kDa

Price:

100 µg/$494

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CRTC1 / MECT1 / TORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119214

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.6 kDa

Price:

100 µg/$710

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Human CRTC1 / MECT1 / TORC1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72274

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.1 kDa

Price:

20 µg/$1,107

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Human CRTC1 / MECT1 / TORC1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72275

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.6 kDa

Price:

20 µg/$1,107

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Human CRTC1 / MECT1 / TORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91896

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.6 kDa

Price:

20 µg/$215

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Human CRTC1 / MECT1 / TORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91897

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.1 kDa

Price:

20 µg/$150

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Human CRTC1 / MECT1 / TORC1 Protein (Recombinant GST, N-terminus) (aa553-634) - LS-G61973

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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