Cre Recombinase

Cre recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the integrase family of site specific recombinase and it is known to catalyse the site specific recombination event between two DNA recognition sites (loxP sites). This 34 base pair (bp) loxP recognition site consists of two 13 bp palindromic sequences which flank an 8bp spacer region. The products of Cre-mediated recombination at loxP sites are dependent upon the location and relative orientation of the loxP sites. Two separate DNA species both containing loxP sites can undergo fusion as the result of Cre mediated recombination. DNA sequences found between two loxP sites are said to be "floxed". In this case the products of Cre mediated recombination depends upon the orientation of the loxP sites. DNA found between two loxP sites oriented in the same direction will be excised as a circular loop of DNA whilst intervening DNA between two loxP sites that are opposingly orientated will be inverted. The enzyme requires no additional cofactors (such as ATP) or accessory proteins for its function. The enzyme plays important roles in the life cycle of the P1 Bacteriophage such as cyclization of the linear genome and resolution of dimeric chromosomes that form after DNA replication.

Cre Recombinase Target Details

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Products

Antibodies (10)

Type

Primary (10)

Target

Cre Recombinase (10)

Reactivity

Bacteriophage (8)

Bacteriophage P1 (1)

Application

IHC (6)

IHC-Fr (5)

IHC-P (5)

WB (10)

ELISA (3)

ICC (6)

IF (1)

IP (6)

Host

rabbit (6)

mouse (3)

goat (1)

Isotype

IgG (1)

IgG1,k (1)

IgG2a (2)

Clonality

monoclonal mc (3)

polyclonal pc (7)

Clone

1D8H3 (1)

Format

Biotin Conjugated (1)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

Unconjugated (6)

Epitope

aa77-343 (1)

Publications

No (8)

Yes (2)

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Cre Recombinase Antibody LS-C179954

(4.0) Rating

(1) Publication(s)

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal Antibody

Reactivity:

Bacteriophage

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.05 ml/$386

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Cre Recombinase Antibody (Biotin) LS-C180305

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal (Biotin) Antibody

Reactivity:

Bacteriophage

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Biotin Conjugated

Price:

0.05 ml/$416

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Cre Recombinase Antibody (DY488) LS-C180307

(4.0) Rating

(1) Publication(s)

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal (DY488) Antibody

Reactivity:

Bacteriophage

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

DY488 Conjugated

Price:

0.05 ml/$416

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Cre Recombinase Antibody (DY550) LS-C180309

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal (DY550) Antibody

Reactivity:

Bacteriophage

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

DY550 Conjugated

Price:

0.05 ml/$416

Select

Cre Recombinase Antibody (DY650) LS-C180306

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal (DY650) Antibody

Reactivity:

Bacteriophage

Applications:

ICC, IHC, IHC-Fr, IHC-P, IP, WB

Format:

DY650 Conjugated

Price:

0.05 ml/$416

• Unconjugated
• Biotin
• DY488
• DY550
• DY650

• Unconjugated
• Biotin
• DY488
• More...
  • DY550
  • DY650

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Cre Recombinase Antibody (aa77-343) LS-C79918

Antibody:

Cre Recombinase Mouse anti-Bacteriophage Monoclonal (aa77-343) Antibody

Reactivity:

Bacteriophage

Applications:

ELISA, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$1,001

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Cre Recombinase Antibody LS-C148264

Antibody:

Cre Recombinase Rabbit anti-Bacteriophage Polyclonal Antibody

Reactivity:

Bacteriophage

Applications:

IP, WB

Format:

Unconjugated

Price:

50 µl/$386

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Cre Recombinase Antibody LS-C204267

Antibody:

Cre Recombinase Goat anti-E. coli Polyclonal Antibody

Reactivity:

Bacteriophage P1

Applications:

WB

Format:

Unconjugated

Price:

600 µg/$409

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Cre Recombinase Antibody (clone 1D8H3) LS-C51638

Antibody:

Cre Recombinase Mouse Monoclonal (1D8H3) Antibody

Applications:

ELISA, WB

Format:

Unconjugated

Price:

40 µg/$307

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Cre Recombinase Antibody LS-C90284

Antibody:

Cre Recombinase Mouse anti-Bacteriophage Monoclonal Antibody

Reactivity:

Bacteriophage

Applications:

ELISA, WB

Format:

Unconjugated

Price:

40 µg/$485

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