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CPA4 is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness.
Gene Name: | carboxypeptidase A4 |
Family/Subfamily: | Exopeptidase , Metallopeptidase M14 |
Synonyms: | CPA4, Carboxypeptidase A4, Carboxypeptidase A3 |
Target Sequences: | NM_016352 NP_057436.2 Q9UI42 |
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