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COUP-TFII / NR2F2

nuclear receptor subfamily 2, group F, member 2

COUP-TFII, a NR2 Hepatocyte NF4-Like receptor, has been shown to affect neuronal development and differentiation, homeostasis in various human tissues, mesenchymal-epithelial interactions during organogenesis, and the development of the cardiovascular system. COUP-TFII interacts with and modulates several nuclear receptors, including estrogen receptor alpha (ER alpha), thyroid hormone receptors (TR), PPAR alpha, and retinoic acid receptors (RAR). Mice lacking COUP-TFII show abnormal heart and vascular development.

Gene Name: nuclear receptor subfamily 2, group F, member 2
Family/Subfamily: NHR , NR2 Hepatocyte NF4-like
Synonyms: NR2F2, ARP1, ARP-1, COUP transcription factor II, COUP-TF II, COUP-TF2, COUP-TFII, COUPTFB, COUPTFII, COUP transcription factor 2, EAR3, NF-E3, SVP40, COUPTF-II, TFCOUP2
Target Sequences: NM_021005 NP_066285.1 P24468

Publications (1)

1
Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution. Fabrizio Orsenigo , Lei Liu Conze , Suvi Jauhiainen, Monica Corada, Francesca Lazzaroni, Matteo Malinverno, Veronica Sundell, Sara Isabel Cunha, Johan Brännström, Maria Ascención Globisch, Claudio Maderna, Maria Grazia Lampugnani, Peetra Ulrica Magnusson, Elisabetta Dejana. eLife. 2020 November;9: [Full Text Article] [PubMed:33138917] [PMC:PMC7609066] Related Antibodies: LS-C356225.

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Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
COUP-TFII / NR2F2 (7)
No (7)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (4)
Human (5)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (1)
COUP-TFII / NR2F2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.4 kDa
100 µg/$494
COUP-TFII / NR2F2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31.3 kDa
100 µg/$494
COUP-TFII / NR2F2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COUP-TFII / NR2F2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COUP-TFII / NR2F2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
31.3 kDa
20 µg/$150
COUP-TFII / NR2F2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
45.4 kDa
20 µg/$150
COUP-TFII / NR2F2 Protein - 12.5% SDS-PAGE of human NR2F2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
72 kDa
2 µg/$439
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).