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COPS4 / CSN4

COP9 signalosome subunit 4

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Gene Name: COP9 signalosome subunit 4
Synonyms: COPS4, CSN4, Signalosome subunit 4, MANOP1, SGN4
Target Sequences: NM_016129 NP_057213.2 Q9BT78

☰ Filters
Products
Antibodies (13)
Primary (13)
COPS4 / CSN4 (13)
Human (12)
Mouse (9)
Rat (9)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (6)
Monkey (6)
Orangutan (6)
Pig (6)
Rabbit (6)
Xenopus (3)
Zebrafish (3)
IHC (2)
IHC-P (1)
WB (13)
ELISA (2)
IP (1)
Peptide-ELISA (1)
rabbit (13)
IgG (9)
polyclonal pc (13)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (7)
aa143-192 (4)
aa53-102 (4)
aa1-310 (1)
aa350-C-term (1)
No (13)
COPS4 / CSN4 Antibody - Detection of Human CSN4 by Western Blot. Samples: Whole cell lysate (50 ug - E; 25 ug - T) from HEK 293T cells that were mock transfected (E) or transfected with a CSN4 expression construct (T). Antibody: Affinity purified rabbit anti-CSN4 antibody used at the indicated concentrations. Detection: Chemiluminescence with a 10 second exposure.
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COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa350-C-term) Antibody
Mouse, Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
COPS4 / CSN4 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
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COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa1-310) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) Antibody
Rat
WB
Unconjugated
100 µl/$424
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
HRP Conjugated
100 µl/$469
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS4 / CSN4 Rabbit anti-Rat Polyclonal (aa53-102) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$469
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
COPS4 / CSN4 Antibody - COPS4 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
COPS4 / CSN4 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).