Complement C4a

complement component 4A (Rodgers blood group)

Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

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Proteins (4)

Type

Recombinant (4)

Target

Complement C4a (4)

Publications

No (4)

Tag

GST, N-terminus (1)

His-GST (2)

His-T7 (1)

Species

Human (2)

Mouse (2)

Source

E. coli (3)

Wheat Germ Extract (1)

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Human Complement C4a Protein (Recombinant His-GST) (aa680-756) - LS-G12093

Source:

E. coli

Tag:

His-GST

Molecular Weight:

41.2 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse Complement C4a Protein (Recombinant His-GST) (aa678-761) - LS-G24002

Source:

E. coli

Tag:

His-GST

Molecular Weight:

39.6 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$3,281

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Mouse Complement C4a Protein (Recombinant His-T7) (aa126-366) - LS-G24154

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.1 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,648

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Human Complement C4a Protein (Recombinant GST, N-terminus) (aa61-170) - LS-G57937

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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