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COMMD1

copper metabolism (Murr1) domain containing 1

Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.

Gene Name: copper metabolism (Murr1) domain containing 1
Synonyms: COMMD1, C2orf5, Protein Murr1, Copper metabolism gene MURR1, MURR1
Target Sequences: Q8N668 Q8N668

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
COMMD1 (7)
No (7)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
COMMD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COMMD1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
COMMD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21 kDa
20 µg/$150
COMMD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21 kDa
100 µg/$494
COMMD1 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
COMMD1 Protein - Purified recombinant protein COMMD1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
21 kDa
20 µg/$1,107
COMMD1 Protein - 12.5% SDS-PAGE of human COMMD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
46.64 kDa
10 µg/$479; 25 µg/$670
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).