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Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.
Gene Name: | copper metabolism (Murr1) domain containing 1 |
Synonyms: | COMMD1, C2orf5, Protein Murr1, Copper metabolism gene MURR1, MURR1 |
Target Sequences: | Q8N668 Q8N668 |
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