Collagen XVII

Collagen Type XVII

Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion. This gene encodes the alpha chain of type XVII collagen. Collagen XVII is a transmembrane protein, like collagen XIII, XXIII and XXV. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Collagen XVII Target Details

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ELISA Kits (2)

Type

Sandwich (2)

Target

Collagen XVII (2)

Reactivity

Human (2)

Format

96-Well Strip Plate (2)

Publications

No (2)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (2)

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Human Collagen XVII (Sandwich ELISA) ELISA Kit - LS-F36535

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human Collagen XVII (Sandwich ELISA) ELISA Kit - LS-F6371

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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