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Collagen II

Type II collagen is the basis for articular cartilage and hyaline cartilage. It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage. Type II collagen does form fibrils. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue.

Collagen II Target Details

Target Name:

Collagen II

Publications (5)

Time-dependent regulation of morphological changes and cartilage differentiation markers in the mouse pubic symphysis during pregnancy and postpartum recovery. Castelucci BG, Consonni SR, Rosa VS, Sensiate LA, Delatti PCR, Alvares LE, Joazeiro PP. PloS one. 2018 April;13:e0195304. (Human) [Full Text Article] [PubMed:29621303] [PMC:PMC5886480]

Effect of Cyclic Dynamic Compressive Loading on Chondrocytes and Adipose-Derived Stem Cells Co-Cultured in Highly Elastic Cryogel Scaffolds. Chen CH, Kuo CY, Chen JP. International journal of molecular sciences. 2018 January;19:pii: E370. (Human) [Full Text Article] [PubMed:29373507] [PMC:PMC5855592]

REAC regenerative treatment efficacy in experimental chondral lesions: a pilot study on ovine animal model. Sanna Passino E, Rocca S, Caggiu S, Columbano N, Castagna A, Fontani V, Rinaldi S. Clinical interventions in aging. 2017 September;12:1471-1479. (Human) [Full Text Article] [PubMed:29066871] [PMC:PMC5604553] Related Antibodies: LS-C18868.

Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation. Megan M Simonds, Amanda R Schlefman, Suzanne M McCahan, Kathleen E Sullivan, Carlos D Rose, AnneMarie C Brescia. Pediatric rheumatology online journal. 2020 November;18:89. [Full Text Article] [PubMed:33198759] [PMC:PMC7670793]

Prevention of lumbar disc degeneration through co-manipulation of insulin-like growth factor 1 and vascular endothelial growth factor. Zuozhou Ye, Shan Zhao, Zuoqing Liu. Annals of Translational Medicine. 2021 Oct;;9:1572. [Full Text Article] [PubMed:34790778] [PMC:PMC8576649]

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