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COLEC12

collectin sub-family member 12

Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid beta in Alzheimer disease.

Gene Name: collectin sub-family member 12
Synonyms: COLEC12, Collectin placenta protein 1, CL-P1, Collectin-12, HCL-P1, NSR2, SCARA4, SRCL, Collectin sub-family member 12
Target Sequences: NM_030781

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
COLEC12 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
Rat (1)
293T Cells (1)
Baculovirus (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
COLEC12 Protein - 12.5% SDS-PAGE of human COLEC12 stained with Coomassie Blue
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Wheat Germ Extract
GST
93.5 kDa
10 µg/$479; 25 µg/$670
COLEC12 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COLEC12 Protein - Purified recombinant protein COLEC12 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
81.3 kDa
20 µg/$1,107
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Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
72.4 kDa
100 µg/$926
COLEC12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
81.3 kDa
20 µg/$150
COLEC12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
81.3 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).