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COL8A2 / Collagen VIII

collagen, type VIII, alpha 2

Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

Gene Name:	collagen, type VIII, alpha 2
Synonyms:	COL8A2, Collagen alpha-2(VIII) chain, Collagen, type VIII, alpha 2, Endothelial collagen, FECD, FECD1, PPCD2, PPCD
Target Sequences:	M60832 AAA62822.1 P25067

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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