Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
COL4A5 / Collagen IV Alpha5 is one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene.
|Gene Name:||collagen, type IV, alpha 5|
|Family/Subfamily:||Collagen , not assigned-Collagen|
|Synonyms:||COL4A5, Alport syndrome, ASLN, ATS, CA54, Collagen, type IV, alpha 5, DA149D17.3, Collagen alpha 5(iv), Collagen alpha-5(IV) chain, DA24A23.1|
|Target Sequences:||NM_000495 NP_000486.1 P29400|
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