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COASY

CoA synthase

Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

Gene Name: CoA synthase
Synonyms: COASY, NBP, Nucleotide binding protein, POV-2, CoA synthase, Coenzyme A synthase, DPCK, UKR1
Target Sequences: NM_025233 NP_079509.5 Q13057

☰ Filters
Products
Proteins (17)
Over-Expression Lysate (9)
Recombinant (8)
COASY (17)
No (17)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (13)
Human (12)
Mouse (1)
293T Cells (5)
E. coli (2)
HEK 293 Cells (8)
Wheat Germ Extract (2)
Purified (1)
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
COASY Protein - 12.5% SDS-PAGE of human COASY stained with Coomassie Blue
Select
Wheat Germ Extract
GST
50.49 kDa
10 µg/$479; 25 µg/$670
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$710
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$215
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
COASY Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
COASY Protein - Purified recombinant protein COASY was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
COASY Protein - Purified recombinant protein COASY was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
COASY Protein - Purified recombinant protein COASY was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
COASY Protein - Purified recombinant protein COASY was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
30 kDa
20 µg/$1,107
COASY Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
COASY Protein - Recombinant Coenzyme A Synthase (COASY) by SDS-PAGE
Select
E. coli
His, N-Terminal
33.3kDa
10 µg/$275; 50 µg/$402; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
COASY Protein - Recombinant Coenzyme A Synthase (COASY) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
24.1kDa
10 µg/$263; 50 µg/$343; 200 µg/$662; 100 µg/$530; 1 mg/$1,657; 500 µg/$1,242; 5 mg/$2,600; 2 mg/$1,832
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).