CNOT7

CCR4-NOT transcription complex, subunit 7

Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

CNOT7 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CNOT7 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G62312

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CNOT7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108012

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

100 µg/$494

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CNOT7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114322

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.6 kDa

Price:

100 µg/$494

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Human CNOT7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71461

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.6 kDa

Price:

20 µg/$1,107

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Human CNOT7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89820

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.6 kDa

Price:

20 µg/$150

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Human CNOT7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89821

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28 kDa

Price:

20 µg/$150

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Human CNOT7 Protein (Recombinant GST) (Full Length) - LS-G33442

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.09 kDa

Price:

10 µg/$479; 25 µg/$670

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