CNOT2

CCR4-NOT transcription complex, subunit 2

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

CNOT2 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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CNOT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113883

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.6 kDa

Price:

100 µg/$494

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Human CNOT2 Protein (Recombinant His, N-Terminal) - LS-G143948

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

59.7 kDa

Price:

50 µg/$419

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Human CNOT2 Protein (Recombinant GST) (Full Length) - LS-G29527

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

85.14 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CNOT2 Protein (Recombinant GST, N-terminus) (aa441-540) - LS-G59423

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CNOT2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84090

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.6 kDa

Price:

20 µg/$150

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