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CMPK2

cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. Also displays broad nucleoside diphosphate kinase activity.

Gene Name: cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Synonyms: CMPK2, Cytidylate kinase 2, Mitochondrial UMP-CMP kinase, TMPK2, TYKi, UMP-CMPK2
Target Sequences: NP_997198.2 Q5EBM0

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
CMPK2 (4)
No (4)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
CMPK2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CMPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
49.3 kDa
20 µg/$215
CMPK2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
49.3 kDa
100 µg/$710
CMPK2 Protein - Purified recombinant protein CMPK2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
49.3 kDa
20 µg/$1,107
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).