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CMPK / CMPK1

cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

Gene Name: cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
Family/Subfamily: Non-protein Kinase , Adenylate kinase
Synonyms: CMPK1, CMPK, Deoxycytidylate kinase, Cytidine monophosphate kinase, RP11-511I2.1, UMP-CMPK, UMP/CMP kinase, Uridine monophosphate kinase, UCK, UMK, UMP-CMP kinase, UMP/CMPK, CMK, Cytidylate kinase, UMPK
Target Sequences: NM_016308 NP_057392.1 P30085

Publications (1)

1
Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients. Liu NQ, De Marchi T, Timmermans A, Trapman-Jansen AM, Foekens R, Look MP, Smid M, van Deurzen CH, Span PN, Sweep FC, Brask JB, Timmermans-Wielenga V, Foekens JA, Martens JW, Umar A. Scientific reports. 2016 August;6:32027. [Full Text Article] [PubMed:27558661] [PMC:PMC4997324] Related Antibodies: LS-C174314.

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Products
Proteins (11)
Over-Expression Lysate (4)
Recombinant (7)
CMPK / CMPK1 (11)
No (11)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (5)
Human (7)
Mouse (2)
293T Cells (2)
Baculovirus (1)
E. coli (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (1)
CMPK / CMPK1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20 kDa
100 µg/$494
CMPK / CMPK1 Protein - 12.5% SDS-PAGE of human UMP-CMPK stained with Coomassie Blue
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Wheat Germ Extract
GST
50.82 kDa
2 µg/$439
CMPK / CMPK1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
CMPK / CMPK1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$598; 20 µg/$405
CMPK / CMPK1 Protein - Purified recombinant protein CMPK1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
20 µg/$1,107
CMPK / CMPK1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CMPK / CMPK1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
20 kDa
20 µg/$150
CMPK / CMPK1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.7 kDa
20 µg/$150
CMPK / CMPK1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.7 kDa
100 µg/$494
CMPK / CMPK1 Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
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Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
24.5 kDa
50 µg/$561
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).