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CLTA / LCA

clathrin, light chain A

Clathrin is the main structural component of the lattice covering the cytoplasmic face of the coated pits and coated vesicles in which specific macromolecules are entrapped in the process of receptor-mediated endocytosis. Clathrin is a large, soluble protein composed of heavy chains and light chains. Two genes, CLTA and CLTB encode the clathrin light chain proteins. The light chains are believed to be regulatory elements in clathrin function. The brain-specific light chain variant contains an insert ecoding 30 amino acids immediately downstream of the region encoding the heavy chain binding domain.

Gene Name: clathrin, light chain A
Synonyms: CLTA, Clathrin light chain A, Clathrin, light chain A, LCA
Target Sequences: NM_007096 NP_009027.1 P09496

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).