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CLINT1 is a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants.
Gene Name: | clathrin interactor 1 |
Synonyms: | CLINT1, CLINT, Enthoprotin, Epsin-4, Epsin-related protein, EPNR, EpsinR, EPN4, KIAA0171, Clathrin interactor 1, ENTH, Epsin 4 |
Target Sequences: | NM_014666 NP_055481.1 Q14677 |
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