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CLIC1 / NCC27
chloride intracellular channel 1
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
| Gene Name: | chloride intracellular channel 1 |
| Family/Subfamily: | Ion Channel , Chloride channel - intracellular |
| Synonyms: | CLIC1, Chloride channel ABP, G6, Nuclear chloride channel-27, p64CLCP, RNCC protein, HRNCC, NCC27 |
| Target Sequences: | NM_001288 NP_001279.2 O00299 |
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