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Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.
Gene Name: | C-type lectin domain family 4, member C |
Synonyms: | CLEC4C, BDCA-2, Blood dendritic cell antigen 2, CD303, CD303 antigen, CLECSF11, CLECSF7, Dendritic cell lectin b, Dendritic lectin, HECL, PRO34150, BDCA2, DLEC |
Target Sequences: | NP_569708.1 Q8WTT0 |
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