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CLDN18 / Claudin 18

claudin 18

CLDN18 / Claudin 18 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: claudin 18
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN18, Claudin 18, Claudin-18, SFTPJ, SFTA5, Surfactant associated 5
Target Sequences: NM_016369 NP_057453.1 P56856

Publications (1)

1
Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway. Norika Chiba, Kenichi Shimada, Shuang Chen, Heather D Jones, Randa Alsabeh, Anatoly V Slepenkin, Ellena Peterson, Timothy R Crother, Moshe Arditi. Journal of immunology (Baltimore, Md. : 1950). 2015 April;194:3840-51. [Full Text Article] [PubMed:25754739] [PMC:PMC4390505] Related Antibodies: LS-C816125.

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Antibodies (25)
ELISA Kits (10)
Proteins (4)
Primary (25)
Recombinant (4)
Sandwich (9)
Sandwich CLIA (1)
CLDN18 / Claudin 18 (39)
Human (23)
Mouse (13)
Rat (12)
Bovine (6)
Chicken (4)
Chimpanzee (6)
Dog (6)
Gibbon (9)
Guinea pig (1)
Horse (6)
Monkey (8)
Pig (6)
Porcine (1)
Rabbit (7)
Sheep (1)
IHC (14)
IHC-P (8)
WB (22)
ELISA (4)
IF (5)
IP (2)
Peptide-ELISA (1)
rabbit (23)
mouse (2)
Product Group
IHCPlus (1)
PathPlus Cancer (1)
PathPlus Cancer Pathology (1)
IgG (16)
IgG2a (1)
monoclonal mc (2)
polyclonal pc (23)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (8)
APC Conjugated (1)
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FITC Conjugated (4)
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Unconjugated (11)
C-Terminus (8)
aa143-192 (4)
No (38)
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Cell Lysates (1)
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GST (1)
GST, N-terminus (1)
His,N-terminus (2)
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E. coli (2)
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Purified (1)
Low endotoxin level (2)
CLDN18 / Claudin 18 Antibody - Human Stomach: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
CLDN18 / Claudin 18 Antibody - Anti-CLDN18 / Claudin 18 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CLDN18 / Claudin 18 Antibody - Anti-CLDN18 / Claudin 18 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CLDN18 / Claudin 18 Antibody - Anti-CLDN18 / Claudin 18 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CLDN18 / Claudin 18 Antibody - Anti-CLDN18 / Claudin 18 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CLDN18 / Claudin 18 Antibody - CLDN18 / Claudin 18 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
CLDN18 / Claudin 18 Antibody - CLDN18 / Claudin 18 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CLDN18 / Claudin 18 Antibody - CLDN18 / Claudin 18 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
CLDN18 / Claudin 18 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
CLDN18 / Claudin 18 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic cancer at dilution 1:100
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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CLDN18 / Claudin 18 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IP
Unconjugated
100 µg/$351
CLDN18 / Claudin 18 Antibody - Immunochemical staining of human Claudin18 in human stomach with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
CLDN18 / Claudin 18 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
CLDN18 / Claudin 18 Protein - 12.5% SDS-PAGE of human CLDN18 stained with Coomassie Blue
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Wheat Germ Extract
GST
54.3 kDa
2 µg/$439
CLDN18 / Claudin 18 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
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CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
IF, IHC, WB
HRP Conjugated
100 µl/$1,017
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CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
IF, IHC, WB
Biotin Conjugated
100 µl/$1,017
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CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
IF, IHC, WB
FITC Conjugated
100 µl/$1,017
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CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
IF, IHC, WB
APC Conjugated
100 µl/$1,017
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CLDN18 / Claudin 18 Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse
IF, IHC, WB
PE Conjugated
100 µl/$1,017
CLDN18 / Claudin 18 Antibody - Western blot analysis of CLDN18 using Jurkat whole cells lysates
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CLDN18 / Claudin 18 Antibody - CLDN18 / Claudin 18 antibody Western blot of Fetal Thymus lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CLDN18 / Claudin 18 Antibody - CLDN18 / Claudin 18 antibody Western blot of Fetal Thymus lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CLDN18 / Claudin 18 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Dog, Rat, Pig, Horse, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 39 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).