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CLDN15 / Claudin 15

claudin 15

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na+, Li+ and K+ ions, but selects against Cl- ions. Plays an important role in paracellular Na+ transport in the intestine and in Na+ homeostasis. Required for normal Na+-dependent intestinal nutrient uptake.

Gene Name: claudin 15
Family/Subfamily: Claudin , not assigned-Claudin
Synonyms: CLDN15, Claudin 15, Claudin-15
Target Sequences: NM_014343 NP_055158.1 P56746

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
CLDN15 / Claudin 15 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
CLDN15 / Claudin 15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
CLDN15 / Claudin 15 Protein - 12.5% SDS-PAGE of human CLDN15 stained with Coomassie Blue
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Wheat Germ Extract
GST
39.82 kDa
2 µg/$439
CLDN15 / Claudin 15 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).